Computational Model of Cell Deforming Under Fluid FLow Based Rolling

Physiological environment in which cells live exertcontinuous mechanical stimuli resulting in deformability which isinvolved in different cell functions. In this context, we conducteda quantitative study on a single cell presenting a mechanicalmodel for cell adhesion with detachment. Specifically, we willexamine the neo-Hookean deformation and the fluid-flowresponsible of cell rolling in bloodstream. Finite element analysiswas used for the modeling of blood cells attached on the vesselwall, in order to detect the inhomogeneities of deformation (e.g.areas at different concentration and different strain). Therefore,the developed model can be used for simulating cell interaction inan endothelial vessel or in different simply and complex scenario.