A new EEG-based methodology is presented for differential diagnosis of the Alzheimer's disease (AD), Mild Cognitive Impairment (MCI), and healthy subjects employing the discrete wavelet transform (DWT), dispersion entropy index (DEI), a recently-proposed nonlinear measurement, and a fuzzy logic-based classification algorithm. The effectiveness and usefulness of the proposed methodology are evaluated by employing a database of measured EEG data acquired from 135 subjects, 45 MCI, 45 AD and 45 healthy subjects. The proposed methodology differentiates MCI and AD patients from HC subjects with an accuracy of 82.6-86.9%, sensitivity of 91 %, and specificity of 87 %.

A New dispersion entropy and fuzzy logic system methodology for automated classification of dementia stages using electroencephalograms

Mammone, Nadia
Membro del Collaboration Group
;
Morabito, Francesco C
Membro del Collaboration Group
;
2021-01-01

Abstract

A new EEG-based methodology is presented for differential diagnosis of the Alzheimer's disease (AD), Mild Cognitive Impairment (MCI), and healthy subjects employing the discrete wavelet transform (DWT), dispersion entropy index (DEI), a recently-proposed nonlinear measurement, and a fuzzy logic-based classification algorithm. The effectiveness and usefulness of the proposed methodology are evaluated by employing a database of measured EEG data acquired from 135 subjects, 45 MCI, 45 AD and 45 healthy subjects. The proposed methodology differentiates MCI and AD patients from HC subjects with an accuracy of 82.6-86.9%, sensitivity of 91 %, and specificity of 87 %.
2021
Alzheimer’s disease
Discrete wavelet transform
Electroencephalograms
Fuzzy logic
Mild cognitive impairment
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.12318/137366
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