Polymers play a key-role in the drug delivery technology. They allow for the controlled release of therapeutic agents under an external stimulus if a sensitive segment is suitable in- corporated in the polymer matrix. Actually, polymer capsules containing noble metal nanostructures are regarded as promising light-responsive drug carriers. Among polymers, poly(methacrylic acid), PMA, offers manifold advantages: i) solubility in water, ii) coordination ability for Ag-Au nanoparti- cles, and iii) ability to act as capping agent. However, the preparation of Ag/PMA nanocolloids in- volves complex procedures the use of reagents with severe environmental impact.
Electrospun Ag/PMA nanofibrous scaffolds as a drug delivery system / G., Neri; S., Spadaro; F., Barreca; Santangelo, Saveria; F., Neri; E., Fazio. - In: CURRENT NANOMATERIALS. - ISSN 2405-4623. - 4:1(2019), pp. 32-38. [10.2174/2405461504666190416144047]
Electrospun Ag/PMA nanofibrous scaffolds as a drug delivery system
SANTANGELO, Saveria;
2019-01-01
Abstract
Polymers play a key-role in the drug delivery technology. They allow for the controlled release of therapeutic agents under an external stimulus if a sensitive segment is suitable in- corporated in the polymer matrix. Actually, polymer capsules containing noble metal nanostructures are regarded as promising light-responsive drug carriers. Among polymers, poly(methacrylic acid), PMA, offers manifold advantages: i) solubility in water, ii) coordination ability for Ag-Au nanoparti- cles, and iii) ability to act as capping agent. However, the preparation of Ag/PMA nanocolloids in- volves complex procedures the use of reagents with severe environmental impact.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
