Jatropha (Jatropha curcas L.) is a plant native of Central and South America, but widely distributed in the wild or semi-cultivated areas in Africa, India, and South East Asia. Although studies are available in literature on the polyphenolic content and bioactivity of Jatropha curcas L., no information is currently available on plants grown in pedoclimatic and soil conditions different from the autochthon regions. The aim of the present work was to characterize the antioxidant system developed by the plant under a new growing condition and to evaluate the polyphenol amount in a methanolic extract of leaves. Along with these analyses we have also tested the antioxidant and cytoprotective activities on lymphocytes. RP-HPLC-DAD analysis of ﬂavonoids revealed a chromatographic proﬁle dominated by the presence of ﬂavone C-glucosydes. Vitexin is the most abundant identiﬁed compound followed by vicenin-2, stellarin-2, rhoifolin, and traces of isovitexin and isorhoifolin. Methanolic extract had high scavenging activity in all antioxidant assays tested and cytoprotectiveactivityonlymphocytesexposedtotertz-buthylhydroperoxide. Theresultshighlighted awell-deﬁnedmechanismofadaptationoftheplantandasigniﬁcantcontentofsecondarymetabolites with antioxidant properties, which are of interest for their potential uses, especially as a rich source of biologically active products.
|Titolo:||Assessment of antioxidant and cytoprotective potential of jatropha (Jatropha curcas) grown in Southern Italy|
|Data di pubblicazione:||2017|
|Appare nelle tipologie:||1.1 Articolo in rivista|